Formulation Development Services

ABT’s formulation group offers feasibility studies to assist in dosage form design, compatibility studies to aid in selection of excipients, product optimization studies, and physicochemical testing. Our scientists have more than 15 years of direct experience solving challenging formulation and drug delivery problems for both small molecules and large biologics. 

We have specialized expertise working with drugs with poor solubility, low bioavailability, short half-life, and gastric intolerability. We routinely perform pre-formulation development studies using liquid, emulsion, suspension, semisolid and aerosol dosage forms.

The team-oriented environment at ABT provides responsive, reliable, and integrated services.  ABT scientists work closely with our clients to ensure they are well prepared for the regulatory submission process so that topics such as formulation optimization, scale-up feasibility, and product performance are well supported.

Services

• Dosage form feasibility studies 
• Formulation development and pre-formulation optimization
• Compatibility studies of active ingredients with excipients, delivery components and packaging components
• Improving product stability
• Solubilizing water-insoluble drugs
• Taste masking/flavoring 
• Container/closure selection 
• Accelerated and long term stability studies 
• Delivery system development

Dosage Forms
We can develop a wide variety of dosage forms including novel technologies when requested:

• Parenteral: Solution, Suspension, and Emulsion 
• Oral:  Solution and Suspension 
• Topical/Transdermal: Gel, Cream, Patch, Ointment, and Lotion 
• Inhalation: Nebulizer and  Nasal Spray